CSMU | CSMU PH | CSMU OSH 

   Molecular Epidemiology Laboratory

　

Mu-Rong Chao  |  Chiung-Wen Hu  |  International Cooperation   |  Core Facilities  |  Chinese Version  |

 

  Mu-Rong Chao, Ph.D  •  Curriculum vitae•  Publications•  On-going projects •

　

  1. Barbara B. Shih, Mark D. Farrar, Andy Vail, Donald Allan, Mu-Rong Chao, Chiung-Wen Hu, George D. D. Jones, Marcus S. Cook and Lesley E. Rhodes. Influence of skin melanisation and ultraviolet radiation on biomarkers of systemic oxidative stress. Free Radical Biology and Medicine, 2020, In press. (SCI; Impact factor = 6.170, Ranking in Biochemistry & Molecular Biology = 41/297 = 13.8%).

  2. Chiung-Wen Hu, Yuan-Jhe Chang, Marcus S. Cooke and Mu-Rong Chao* (Corresponding Author). DNA crosslinkomics: A tool for the comprehensive assessment of interstrand crosslinks using high resolution mass spectrometry. Analytical Chemistry, 2019, 91, 15193-15203. (SCI; Impact factor = 6.785, Ranking in Chemistry, analytical = 7/86 = 8.1%).

  3. Marcus S. Cooke, Chiung-Wen Hu and Mu-Rong Chao* (Co-corresponding Author). Editorial: Mass spectrometry for adductomic analysis. Frontiers in Chemistry, 2019, 7, 794. (SCI; Impact factor = 3.693, Ranking in Chemistry, multidisciplinary = 57/177 = 32.2%).

  4. Chiung-Wen Hu, Yuan-Jhe Chang, Cheng-Chieh Yen, Jian-Lian Chen, Rajendra Bose Muthukumaran and Mu-Rong Chao* (Corresponding Author) 15N-labelled nitrite/nitrate tracer analysis by LC-MS/MS: Urinary and fecal excretion of nitrite/nitrate following oral administration to mice. Free Radical Biology and Medicine, 2019, 143, 193-202. (SCI; Impact factor = 6.170, Ranking in Biochemistry & Molecular Biology = 41/297 = 13.8%).

  5. Ying-Ming Shih, Marcus S. Cooke, Chih-Hong Pan, Mu-Rong Chao* (Co-corresponding Author) and Chiung-Wen Hu*. Clinical relevance of guanine-derived urinary biomarkers of oxidative stress, determined by LC-MS/MS. Redox Biology, 2019, 20, 556-565. (SCI; Impact factor = 9.986, Ranking in Biochemistry & Molecular Biology = 20/297 = 6.7%).

  6. Hueiwang Anna Jeng, Wen-Yi Lin, Mu-Rong Chao and Chih-Hong Pan. Semen quality and sperm DNA damage associated with oxidative stress in relation to exposure to polycyclic aromatic hydrocarbons. Journal of Environmental Science and Health Part A Toxic/Hazardous Substances & Environmental Engineering, 2018, 53, 1221-1228. (SCI; Impact factor = 1.724, Ranking in Environmental Sciences = 183/265 = 69.1%).

  7. Marcus S. Cooke, Chiung-Wen Hu, Yuan-Jhe Chang and Mu-Rong Chao* (Corresponding Author). Urinary DNA adductomics – A novel approach for exposomics. Environment International, 2018, 121, 1033-1038. (SCI; Impact factor = 7.577, Ranking in Environmental Sciences = 18/265 = 6.8%).

  8. Mu-Rong Chao, Marcus S. Cooke, Chung-Yih Kuo, Chih-Hong Pan, Hung-Hsin Liu, Hao-Jan Yang, Szu-Chieh Chen, Yi-Chen Chiang and Chiung-Wen Hu. Children are particularly vulnerable to environmental tobacco smoke exposure: Evidence from biomarkers of tobacco-specific nitrosamines, and oxidative stress. Environment International, 2018, 120, 238-245. (SCI; Impact factor = 7.577, Ranking in Environmental Sciences = 18/265 = 6.8%).

  9. Chiung-Wen Hu, Marcus S. Cooke, Yuan-Jhe Chang and Mu-Rong Chao* (Corresponding Author). Direct-acting DNA ethylating agents associated with tobacco use primarily originate from the tobacco itself, not combustion. Journal of Hazardous Materials, 2018, 358, 397-404. (SCI; Impact factor = 9.038; Ranking in Environmental Sciences = 8/265 = 3.0%).

  10. Yuan-Jhe Chang, Marcus S. Cooke, Chiung-Wen Hu* and Mu-Rong Chao* (Co-corresponding Author). Novel approach to integrated DNA adductomics for the assessment of in vitro and in vivo environmental exposures. Archives of Toxicology, 2018, 92, 2665-2680. (SCI; Impact factor = 5.059, Ranking in Toxicology = 9/92 = 9.8%).

  11. Chiung-Wen Hu, Yuan-Jhe Chang, Jian-Lian Chen, Yu-Wen Hsu and Mu-Rong Chao* (Corresponding Author). Sensitive detection of 8-nitroguanine in DNA by chemical derivatization coupled with online solid-phase extraction LC-MS/MS. Molecules, 2018, 23, 605. (SCI; Impact factor = 3.267; Ranking in Chemistry, multidisciplinary = 70/177 = 39.5%).

  12. Tsu-Shing Wang, Cheng-Ping Lin, Yu-Pong Chen, Mu-Rong Chao, Chien-Chun Li and Kai-Li Liu. CYP450-mediated mitochon drial ROS production involved in arecoline N-oxide-induced oxidative damage in liver cell lines. Environmental Toxicology, 2018, 33, 1029-1038. (SCI; Impact factor = 3.118; Ranking in Water Resources = 21/94 = 22.3%).

  13. Chiung-Wen Hu, Yuan-Jhe Chang, Yu-Wen Hsu, Jian-Lian Chen, Tsu-Shing Wang and Mu-Rong Chao* (Corresponding Author). Comprehensive analysis of the formation and stability of peroxynitrite derived 8-nitroguanine by LC-MS/MS: Strategy for the quantitative analysis of cellular 8-nitroguanine. Free Radical Biology and Medicine, 2016, 101, 348-355. (SCI; Impact factor = 6.170, Ranking in Biochemistry & Molecular Biology = 41/297 = 13.8%).

  14. Mu-Rong Chao, Chiung-Wen Hu and Jian-Lian Chen. Glass substrates crosslinked with tetracycline-imprinted polymeric silicate and CdTe quantum dots as fluorescent sensors. Analytica Chimica Acta, 2016, 925, 61-69. (SCI; Impact factor = 5.977, Ranking in Chemistry, analytical = 10/86 = 11.6).

  15. Chiung-Wen Hu, Ying-Ming Shih, Hung-Hsin Liu, Yi-Chen Chiang, Chih-Ming Chen and Mu-Rong Chao* (Corresponding Author). Elevated urinary levels of carcinogenic N-nitrosamines in patients with urinary tract infections measured by isotope dilution online SPE LC-MS/MS. Journal of Hazardous Materials, 2016, 310, 207-216. (SCI; Impact factor = 9.038; Ranking in Environmental Sciences = 8/265 = 3.0%).

  16. Mu-Rong Chao, Chiung-Wen Hu and Jian-Lian Chen. Fluorometric determination of copper(II) using CdTe quantum dots coated with 1-(2-thiazolylazo)-2-naphthol and an ionic liquid. Microchim Acta, 2016, 183, 1323-1332 (SCI; Impact factor = 6.232, Ranking in Chemistry, analytical = 9/86 = 10.4%).

  17. Mu-Rong Chao, Ying-Ming Shih, Yu-Wen Hsu, Hung-Hsin Liu, Yuan-Jhe Chang, Bo-Huei Lin and Chiung-Wen Hu. Urinary nitrite/nitrate ratio measured by isotope-dilution LC-MS/MS as a tool to screen for urinary tract infections. Free Radical Biology and Medicine, 2016, 93, 77-83. (SCI; Impact factor = 6.170, Ranking in Biochemistry & Molecular Biology = 41/297 = 13.8%).

  18. Hueiwang Anna Jeng, Chih-Hong Pan, Mu-Rong Chao, Chien-Chih Chiu, Guodong Zhou, Chon-Kit Chou and Wen-Yi Lin. Sperm quality and DNA integrity of coke oven workers exposed to polycyclic aromatic hydrocarbons. International Journal of Occupational Medicine and Environmental Health, 2016, 29, 915–926. (SCI; Impact factor = 1.541; Ranking in Public, Environmental & Occupational Health = 135/193 = 69.9%).

  19. Chiung-Wen Hu and Mu-Rong Chao* (Corresponding Author). Measurement of urinary biomarkers of oxidative stress. Chung Shan Medical Journal, 2015, 26, 59-66.

  20. Mu-Rong Chao, Yu-Wen Hsu, Hung-Hsin Liu, Jia-Hong Lin and Chiung-Wen Hu. Simultaneous detection of 3-nitrotyrosine and 3-nitro-4-hydroxyphenylacetic acid in human urine by online SPE LC-MS/MS and their association with oxidative and methylated DNA lesions. Chemical Research in Toxicology, 2015, 28, 997-1006. (SCI; Impact factor = 3.184, Ranking in Toxicology = 34/92 = 37.0%).

  21. Chiung-Wen Hu, Marcus S. Cooke, Yi-Hung Tsai and Mu-Rong Chao* (Corresponding Author). 8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2­-deoxyguanosine concentrations in various human body fluids: implications for their measurement and interpretation. Archives of Toxicology, 2015, 92, 2665-2680. (SCI; Impact factor = 5.059, Ranking in Toxicology = 9/92 = 9.8%).

  22. Chiung-Wen Hu, Jian-Lian Chen, Yu-Wen Hsu, Cheng-Chieh Yen and Mu-Rong Chao* (Corresponding Author). Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC-MS/MS: first evidence of DNA methylation in Caenorhabditis elegans. Biochemical Journal, 2015, 465:39-47. (SCI; Impact factor = 4.097, Ranking in Biochemistry & Molecular Biology = 75/297 = 32.0%).

  23. Hueiwang Anna Jeng, Chih-Hung Pan and Mu-Rong Chao. Urinary DNA lesions as a biomarker for assessing male reproductive health. AIMS Environmental Science, 2015, 2:565-576. (ESCI)

  24. Hueiwang Anna Jeng, Mu-Rong Chao, Ruei-Nian Li, Chih-Hung Pan and Wen-Yi Lin. Measurement of 8-oxo-7,8-dihydro-2’-deoxyguanosine in human semen and urine by isotope-dilution liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction: comparison with a commercial available enzyme-linked immunosorbent assay. Andrology, 2015, S1:001.

  25. Hueiwang Anna Jeng, Chih-Hong Pan, Mu-Rong Chao and Wen-Yi Lin. Sperm DNA oxidative damage and DNA adducts. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 2015. 794:75-82. (SCI; Impact factor = 2.506, Ranking in Toxicology = 54/92 = 58.7%).

  26. Mu-Rong Chao, Chiung-Wen Hu and Jian-Lian Chen. Comparative syntheses of tetracycline-imprinted polymeric silicate and acrylate on CdTe quantum dots as fluorescent sensors. Biosensors & Bioelectronics, 2014, 61:471-477. (SCI; Impact factor = 10.257, Ranking in Chemistry, analytical = 1/86 = 1.2%).

  27. Yu-Hu Chiou, Ruey-Hong Wong, Mu-Rong Chao, Chih-Yi Chen, Saou-Hsing Liou and Huei Lee. Nickel accumulation in lung tissues is associated with increased risk of p53 mutation in lung cancer patients. Environmental and Molecular Mutagenesis, 2014, 55:624-632. (SCI; Impact factor = 3.131, Ranking in Environmental Sciences = 96/265 = 36.2%).

  28. Mu-Rong Chao, Domniki Fragou, Panos Zanos, Chiung-Wen Hu, Alexis Bailey, Sofia Kouidou and Leda Kovatsi. Epigenetically modified nucleotides in chronic heroin and cocaine treated mice. Toxicology Letters, 2014, 229:451-457. (SCI; Impact factor = 3.569, Ranking in Toxicology = 20/92 = 21.7%).

  29. Mu-Rong Chao, Chiung-Wen Hu and Jian-Lian Chen. Fluorescent turn-on detection of cysteine using a molecularly imprinted polyacrylate linked to allylthiol-capped CdTe quantum dots. Microchim Acta, 2014, 181:1085–1091 (SCI; Impact factor = 6.232, Ranking in Chemistry, analytical = 9/86 = 10.4%).

  30. Chiung-Wen Hu, Yu-Wen Hsu, Jian-Lian Chen, Lai-Man Tam and Mu-Rong Chao* (Corresponding Author). Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions. Archives of Toxicology, 2014, 88:291-299. (SCI; Impact factor = 5.059, Ranking in Toxicology = 9/92 = 9.8%).

  31. Yuan-Jhe Chang, Mu-Rong Chao, Su-Chin Chen, Chih-Hong Chen and Yan-Zin Chang. A high-throughput method based on microwave-assisted extraction and liquid chromatography-tandem mass spectrometry for simultaneous analysis of amphetamines, ketamine, opiates, and their metabolites in hair. Analytical and Bioanalytical Chemistry, 2014, 406:2445-2455. (SCI; Impact factor = 3.637, Ranking in Chemistry, analytical = 18/86 = 20.9%).

  32. Mu-Rong Chao* (Corresponding Author), Pavel Rossner Jr., Siamak Haghdoost, Hueiwang Anna Jeng and Chiung-Wen Hu. Nucleic acid oxidation in human health and disease. Oxidative Medicine and Cellular Longevity, 2013, 2013:368651. (SCI; Impact factor = 4.936, Ranking in Cell Biology = 52/190 = 27.4%)

  33. Chiung-Wen Hu, Huei Lee, Jian-Lian Chen, Yi-Jie Li and Mu-Rong Chao* (Corresponding Author). Optimization of global DNA methylation measurement by LC-MS/MS and its application in lung cancer patient. Analytical and Bioanalytical Chemistry, 2013, 405, 8859-8869. (SCI; Impact factor = 3.307, Ranking in Chemistry, analytical = 15/80 = 18.8%)

  34. Lars Barregård, Peter Moller, Trine Henriksen, Vilas Mistry, Gudrun Koppen, Pavel Rossner, Radim Sram, Allan Weimann, Henrik Poulsen, Robert Nataf, Roberta Andreolli, Paola Manini, Timothy H Marczylo, Patricia Lam, Mark Dennis Evans, Hiroshi Kasai, Kazuaki Kawai, Yun-Shan Li, Kazuo Sakai, Raj Singh, Friederike Teichert, Peter Farmer, Rafal Rozalski, Daniel Gackowski, Agnieszka Siomek, Guillermo Saez, Concha Cerda, Karin Broberg, Christian Lund, Mohammad Hossain, Siamak Haghdoost, Chiung-Wen Hu, Mu-Rong Chao, Kuen-Yuh Wu, Nilufer Senduran, Hilmi Orhan, Raymond J Smith, Regina Santella, Yali Su, Czarina Cortez, Susan Yeh, Ryszard Olinski, Steffen Loft, Marcus Stanley Cooke. Human and methodological sources of variability in the measurement of urinary 8-oxo-7,8-dihydro-2’-deoxyguanosine. Antioxidants & Redox Signaling, 2013, 18, 2377-2391. (SCI; Impact factor = 6.53, Ranking in Endocrinology & Metabolism = 12/143 = 8.4%).

  35. Hueiwang Anna Jeng, Chih-Hong Pan and Mu-Rong Chao. 1-Hydroxypyrene as a biomarker for assessing the effects of exposure to polycyclic aromatic hydrocarbons on semen quality and sperm DNA integrity. Journal of Environmental Science and Health, Part A: Toxic/Hazardous Substances and Environmental Engineering, 2013, 48, 152-158. (SCI; Impact factor = 1.561, Ranking in Environmental Sciences = 148/241 = 61.4%).

  36. Mu-Rong Chao, Yan-Zin Chang and Jian-Lian Chen. Hydrophilic ionic liquid-passivated CdTe quantum dots for mercury ion detection. Biosensors & Bioelectronics, 2013, 42, 397-402. (SCI; Impact factor = 8.173, Ranking in Chemistry, analytical = 2/80 = 2.5%).

  37. Chiung-Wen Hu and Mu-Rong Chao* (Corresponding Author). Direct-acting DNA alkylating agents present in aqueous extracts of areca nut and its products. Chemical Research in Toxicology, 2012, 25, 2386-2392. (SCI; Impact factor = 3.432, Ranking in Chemistry, medicinal = 17/59 = 28.8%).

  38. Chiung-Wen Hu, Hung-Hsin Liu, Yi-Jie Li and Mu-Rong Chao* (Corresponding Author). Direct analysis of 5-methylcytosine and 5-methyl-2'-deoxycytidine in human urine by isotope dilution LC-MS/MS: correlations with N-methylated purines and oxidized DNA lesions. Chemical Research in Toxicology, 2012, 25, 462-470. (SCI; Impact factor = 3.432, Ranking in Chemistry, medicinal = 17/59 = 28.8%).

  39. Chiung-Wen Hu, Chih-Ming Chen, Hsin Hui Ho and Mu-Rong Chao* (Corresponding Author). Simultaneous quantification of methylated purines in DNA by isotope dilution LC-MS/MS coupled with automated solid-phase extraction. Analytical and Bioanalytical Chemistry, 2012, 402, 1199-1208. (SCI; Impact factor = 3.307, Ranking in Chemistry, analytical = 15/80 = 18.8%).

  40. Jian-Lian Chen, Yu-Jie Huang, Chih-Hong Pan, Chiung-Wen Hu* and Mu-Rong Chao* (Co-corresponding Author). Determination of urinary malondialdehyde by isotope dilution LC-MS/MS with automated solid-phase extraction: A cautionary note on derivatization optimization. Free Radical Biology and Medicine, 2011, 51, 1823-1829. (SCI; Impact factor = 6.02, Ranking in Biochemistry & Molecular Biology = 39/293 = 13.3%).

  41. Chiung-Wen Hu, Bo-Huei Lin and Mu-Rong Chao* (Corresponding Author). Quantitative determination of urinary N3-methyladenine by isotope-dilution LC-MS/MS with automated solid-phase extraction. International Journal of Mass Spectrometry, 2011, 304, 68-73. (SCI; Impact factor = 1.826, Ranking in Spectroscopy = 21/43 = 48.8%).

  42. Chiung-Wen Hu, Yan-Zin Chang, Hsiao-Wen Wang and Mu-Rong Chao* (Corresponding Author). High-throughput simultaneous analysis of five urinary metabolites of areca nut and tobacco alkaloids by isotope-dilution LC-MS/MS with on-line solid-phase extraction. Cancer Epidemiology, Biomarkers & Prevention. 2010, 19(10), 2570-2581. (SCI; Impact factor = 4.554, Ranking in Public, Environmental & Occupational Health = 13/181 = 7.2%).

  43. Chiung-Wen Hu and Mu-Rong Chao* (Corresponding Author). Assessment of oxidative stress using urinary 8-oxodG and 8-oxo-Gua levels. Clinical Laboratory International. 2010, 34, 12-14. (Cover Article; Invited Article).

  44. Chiung-Wen Hu, Mu-Rong Chao and Ciao-Han Sie. Urinary analysis of 8-oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine by isotope-dilution LC-MS/MS with automated solid-phase extraction: study of 8-oxo-7,8-dihydroguanine stability. Free Radical Biology and Medicine, 2010, 48(1), 89-97. (SCI; Impact factor = 6.02, Ranking in Biochemistry & Molecular Biology = 39/293 = 13.3%).

  45. Chiung-Wen Hu, Yu-Jie Huang, Yi-Jie Li and Mu-Rong Chao* (Corresponding Author). Correlation between concentrations of 8-oxo-7,8-dihydro-2'-deoxyguanosine in urine, plasma and saliva measured by on-line solid-phase extraction LC-MS/MS. Clinica Chimica Acta, 2010, 411 (17-18), 1218-1222. (SCI; Impact factor = 2.926, Ranking in Medical Laboratory Technology = 8/30= 26.7%).

  46. Chiung-Wen Hu, Cheng-Chieh Yen, Yeou-Lih Huang, Chih-Hong Pan, Fung-Jou Lu and Mu-Rong Chao* (Corresponding Author). Oxidatively damaged DNA induced by humic acid and arsenic in maternal and neonatal mice. Chemosphere, 2010, 79(1), 93-99. (SCI; Impact factor = 4.427, Ranking in Environmental Sciences = 35/242 = 14.5%).

  47. ESCULA [European Standards Committee on Urinary (DNA) Lesion Analysis], Mark D. Evans, Ryszard Olinski, Steffen Loft, Marcus S. Cooke. Toward consensus in the analysis of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a noninvasive biomarker of oxidative stress. FASEB Journal, 2010, 24(1), 1249-1260. (Group Authors, SCI; Impact factor = 5.595, Ranking in Biology = 8/85 = 9.4%).

  48. I-Chen Wu, Ping-Ho Chen, Chien-Jen Wang, Deng-Chyang Wu, Shih-Meng Tsai, Mu-Rong Chao, Bai-Hsiun Chen, Hei-Hwa Lee, Chien-Hung Lee and Ying-Chin Ko. Quantification of blood betel quid alkaloids and urinary 8-hydroxydeoxyguanosine in humans and their association with betel chewing habits. Journal of Analytical Toxicology, 2010, 34(6), 325-31. (SCI; Impact factor = 2.599, Ranking in Chemistry, Analytical = 27/81 = 33.3%).

  49. Mu-Rong Chao, Yan-Zin Chang, Ruey-Hong Wong and Chiung-Wen Hu. Time course evaluation of N-nitrosodialkylamines-induced DNA alkylation and oxidation in liver of mosquito fish. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2009, 660(1-2), 33-39. (SCI; Impact factor = 4.440, Ranking in Toxicology = 11/87 = 12.4%).

  50. I-Hsin Lin, Mu-Rong Chao, Chiung-Wen Hu, Ming-Lin Ho, Jo-Yun Huang, Hong-Shen Lee, Chun-Chieh Chen and Ruey-Hong Wong. Modification of urinary N7-methylguanine excretion in smokers by glutathione-S-transferase M1 polymorphism. Toxicology, 2009, 260(1-3), 1-6. (SCI; Impact factor = 3.745, Ranking in Toxicology = 14/87 = 16.1%).

  51. Mu-Rong Chao and Jian-Lian Chen. Efficient stripping of photoresist on metallized wafers by a pause flow of supercritical fluid. Journal of Hazardous Materials, 2009, 169(1-3), 153-157. (SCI; Impact factor = 4.173; Ranking in Environmental Sciences = 16/215 = 7.4%).

  52. Mu-Rong Chao, Chien-Jen Wang, Ming-Tsang Wu, Chih-Hong Pan, Chung-Yih Kuo, Hao-Jan Yang, Louis W. Chang and Chiung-Wen Hu. Repeated measurements of urinary methylated/oxidative DNA lesions, acute toxicity and mutagenicity in coke-oven workers. Cancer Epidemiology, Biomarkers & Prevention, 2008, 17(12), 3381-3389. (SCI; Impact factor = 4.324, Ranking in Public, Environmental & Occupational Health = 12/160 = 7.5%).

  53. Hsi-Hsien Yang, Shu-An Lee, Dennis P. H. Hsieh, Mu-Rong Chao and Che-Yu Tung. PM2.5 and Associated Polycyclic Aromatic Hydrocarbon and Mutagenicity Emissions from Motorcycles. Bulletin of Environmental Contamination and Toxicology, 2008, 81(4), 412-415. (SCI; impact factor = 1.216, Ranking in Environmental Sciences = 138/215= 64.2%).

  54. Ruey-Hong Wong, Chiung-Wen Hu, Ching-Ying Yeh, Mu-Rong Chao, Chin-Chun Chen, Jun-Huang Huang, Shih-Hsien Chang, Shin-I Lee, Hong-Shen Lee. Sulfotransferase 1A1 and glutathione S-transferase P1 genetic polymorphisms modulate the levels of urinary 8-hydroxy-2’-deoxyguanosine in betel quid chewers. Archives of Toxicology, 2008, 82(5), 313-321. (SCI; Impact factor = 5.078, Ranking in Toxicology = 9/87 = 10.3%).

  55. Chung-Yih Kuo, Yu-Huan Yang, Mu-Rong Chao and Chiung-Wen Hu. The exposure of temple workers to polycyclic aromatic hydrocarbons. Science of the Total Environment, 2008, 401(1-3), 44-50. (SCI; impact factor = 3.163, Ranking in Environmental Sciences = 40/215 = 18.6%).

  56. Mu-Rong Chao, Cheng-Chieh Yen and Chiung-Wen Hu. Prevention of artifactual oxidation in determination of cellular 8-oxo-7,8-dihydro-2'-deoxyguanosine by isotope-dilution LC-MS/MS with automated solid-phase extraction. Free Radical Biology and Medicine, 2008, 44(3), 464–473. (SCI; Impact factor = 5.710, Ranking in Biochemistry & Molecular Biology = 45/291 = 15.5%).

  57. Hsi-Hsien Yang, Shu-Mei Chien, Hui-Ling Lee, Mu-Rong Chao, Hong-Wei Luo, Dennis P.H. Hsieh and Wen-Jhy Lee. Emission of trans,trans-2,4-decadienal from restaurant exhausts to the atmosphere. Atmospheric Environment, 2007, 41, 5327-5333. (SCI; Impact factor = 3.062; Ranking in Environmental Sciences = 44/215 = 20.5%).

  58. Mu-Rong Chao, Chien-Jen Wang, Cheng-Chieh Yen, Hsi-Hsien Yang, Yao-Cheng Lu, Louis W. Chang and Chiung-Wen Hu. Simultaneous determination of N7-alkylguanines in DNA by isotope-dilution LC-tandem MS coupled with automated solid-phase extraction and its application to a small fish model. Biochemical Journal, 2007, 402(3), 483-490. (SCI; Impact factor = 4.779, Ranking in Biochemistry & Molecular Biology = 61/291 = 21.0%).

  59. Hsi-Hsien Yang, Cheng-Hsien Tsai, Mu-Rong Chao, Yi-Ling Su and Shu-Mei Chien. Source identification and size distribution of atmospheric polycyclic aromatic hydrocarbons during rice straw burning period. Atmospheric Environment, 2006, 40, 1266-1274. (SCI; Impact factor = 3.062; Ranking in Environmental Sciences = 44/215 = 20.5%).

  60. Chiung-Wen Hu, Chih-Hong Pan, Yeou-Lih Huang, Ming-Tsang Wu, Louis W. Chang, Chien-Jen Wang and Mu-Rong Chao* (Corresponding Author). Effects of arsenic exposure among semiconductor workers: A cautionary note on urinary 8-oxo-7,8-dihydro-2’-deoxyguanosine. Free Radical Biology and Medicine, 2006, 40(7), 1273-1278. (SCI; Impact factor = 5.710, Ranking in Biochemistry & Molecular Biology = 45/291 = 15.5%).

  61. Chiung-Wen Hu, Chien-Jen Wang, Louis W. Chang and Mu-Rong Chao* (Corresponding Author). Clinical-scale high-throughput analysis of urinary 8-Oxo-7,8-dihydro-2'-deoxyguanosine by isotope-dilution LC-MS/MS with on-line solid-phase extraction. Clinical Chemistry, 2006, 52(7), 1381-1388. (SCI; Impact factor = 7.768, Ranking in Medical Laboratory Technology = 1/29= 3.5%).

  62. Mu-Rong Chao, Chien-Jen Wang, Louis W. Chang and Chiung-Wen Hu. Quantitative determination of urinary N7-ethylguanine in smokers and nonsmokers using an isotope dilution liquid chromatography/tandem mass spectrometry with on-line analyte enrichment. Carcinogenesis. 2006, 27(1), 146-151. (SCI; Impact factor = 5.266, Ranking in Oncology = 32/202 = 15.8%).

  63. Mu-Rong Chao, Chien-Jen Wang, Hsi-Hsien Yang, Louis W. Chang and Chiung-Wen Hu. Rapid and sensitive quantification of urinary N7-methylguanine by isotope-dilution liquid-chromatography electrospray ionization tandem mass spectrometry with on-line solid-phase extraction. Rapid Communications in Mass Spectrometry, 2005, 19(17), 2427-2432. (SCI; Impact factor = 2.642, Ranking in Spectroscopy = 13/44 = 29.5%).

  64. Hsi-Hsien Yang, Shu-Mei Chien, Mu-Rong Chao and Chi-Chwen Lin. Particle size distribution of polycyclic aromatic hydrocarbons in motorcycle exhaust emissions. Journal of Hazardous Materials, 2005, 125(1-3), 154-159. (SCI; Impact factor = 4.173; Ranking in Environmental Sciences = 16/215 = 7.4%).

  65. Hsi-Hsien Yang, Shu-Mei Chien, Mu-Rong Chao and Ya-Fen Wang. Size distribution of particulate polycyclic aromatic hydrocarbons in the diluted four-stroke motorcycle exhausts. Aerosol and Air Quality Research, 2005, 5(2), 225-235. (SCI; Impact factor = 2.664; Ranking in Environmental Sciences = 65/215 = 30.2%).

  66. Chiung-Wen Hu, Ming-Tsang Wu, Mu-Rong Chao, Chih-Hong Pan, Chien-Jen Wang, James A. Swenberg and Kuen-Yuh Wu. Comparison of analyses of urinary 8-hydroxy-2’-deoxyguanosine by isotope-dilution liquid chromatography with electrospray tandem mass spectrometry and by enzyme-linked immunosorbent assay. Rapid Communications in Mass Spectrometry, 2004, 18(4), 505-510. (SCI; Impact factor = 2.642, Ranking in Spectroscopy = 13/44 = 29.5%; ISI Highly Cited Paper).

  67. Mu-Rong Chao, Chiung-Wen Hu, Yi-lung Chen, Gou-Ping Chang-Chien, Wen-Jhy Lee, Louis W. Chang and Kuen-Yuh Wu. Approaching gas-particle partitioning equilibrium of atmospheric PCDD/Fs with increasing distance from an incinerator: measurements and observations on modeling. Atmospheric Environment, 2004, 38(10), 1501-1510. (SCI; Impact factor = 3.062; Ranking in Environmental Sciences = 44/215 = 20.5%).

  68. Mu-Rong Chao, Chiung-Wen Hu, Hwong-Wen Ma, Gou-Ping Chang-Chien, Wen-Jhy Lee, Louis W. Chang and Kuen-Yuh Wu. Size distribution of particle-bound polychlorinated dibenzo-p-dioxins and dibenzofurans in the ambient air of a municipal incinerator. Atmospheric Environment, 2003, 37(35), 4945-4954. (SCI; Impact factor = 3.062; Ranking in Environmental Sciences = 44/215 = 20.5%).

  69. Chiung-Wen Hu, Mu-Rong Chao, Kuen-Yuh Wu, Gou-Ping Chang-Chien, Wen-Jhy Lee and Louis W. Chang. Characterization of multiple airborne particulate metals in the surroundings of a municipal waste incinerator in Taiwan. Atmospheric Environment, 2003, 37(20), 2845-2852. (SCI; Impact factor = 3.062; Ranking in Environmental Sciences = 44/215 = 20.5%).

  70. Ta-Chang Lin, Feng-Hsiang Chang, Jue-Hsien Hsieh, How-Ran Chao and Mu-Rong Chao. Characteristics of polycyclic aromatic hydrocarbons and total suspended particulate in indoor and outdoor atmosphere of a Taiwanese temple. Journal of Hazardous Materials, 2002, 95(1-2), 1-12. (SCI; Impact factor = 4.173; Ranking in Environmental Sciences = 16/215 = 7.4%)

  71. Ta-Chang Lin and Mu-Rong Chao. Assessing the influence of methanol-containing additive on biological characteristics of diesel exhaust emissions using microtox and mutatox assays. Science of the Total Environment, 2002, 284(1-3), 61-74. (SCI; impact factor = 3.163, Ranking in Environmental Sciences = 40/215 = 18.6%).

  72. Mu-Rong Chao, Ta-Chang Lin, How-Ran Chao. Feng-Hsiang Chang and Chung-Bang Chen. Effects of methanol-containing diesel additives on emission characteristics of a heavy-duty diesel engine. Science of the Total Environment, 2001, 279(1-3), 167-179. (SCI; impact factor = 3.163, Ranking in Environmental Sciences = 40/215 = 18.6%).

  73. Ta-Chang Lin, Feng-Hsiang Chang, Jue-Hsien Hsieh, How-Ran Chao and Mu-Rong Chao. Environmental exposure to polycyclic aromatic hydrocarbons and total suspended particulate in a Taiwanese temple. Bulletin of Environmental Contamination and Toxicology, 2001, 67(3), 332-338. (SCI; impact factor = 1.216, Ranking in Environmental Sciences = 138/215 = 64.2%).

  74. Feng-Hsiang Chang, Ta-Chang Lin, How-Ran Chao and Mu-Rong Chao. A study on losses of PAHs during sample concentrate for chromatographic analysis: evaporation with a stream of nitrogen. International Journal of Environmental Analytical Chemistry, 2001, 80(1), 13-26. (SCI; Impact factor = 1.321; Ranking in Environmental Sciences = 125/215 = 58.1%)

  75. Jia-Nan Shieh, Mu-Rong Chao and Chung-Yuan Chen. Statistical comparisons of the no-observed-effect concentration and the effective concentration at 10% inhibition (EC10) in algal toxicity tests. Water Science and Technology, 2001, 43(2), 141-146. (SCI; Impact factor = 1.212; Ranking in Ranking in Environmental Sciences = 138/215 = 64.7%)

  76. Mu-Rong Chao and Chung-Yuan Chen. Discrepancies between different response parameters in batch and continuous algal toxicity tests. Journal of Hazardous Materials, 2001, 82(2), 129-136. (SCI; Impact factor = 4.173; Ranking in Environmental Sciences = 16/215 = 7.4%)

  77. Mu-Rong Chao and Chung-Yuan Chen. Effects of inoculum's mean cell volume on algal toxicity tests. Water Science and Technology, 2000, 42(7-8), 291–296. (SCI; Impact factor = 1.212; Ranking in Ranking in Environmental Sciences = 138/215 = 64.7%)

  78. How-Ran Chao, Ta-Chang Lin, Mu-Rong Chao, Feng-Hsiang Chang, Chao-I Huang and Chung-Bang Chen. Effect of methanol-containing additive on the emission of carbonyl compounds from a heavy-duty diesel engine. Journal of Hazardous Materials, 2000, 73(1), 39-54. (SCI; Impact factor = 4.173; Ranking in Environmental Sciences = 16/215 = 7.4%)

  79. Mu-Rong Chao and Chung-Yuan Chen. No-observed effect concentrations in batch and continuous algal toxicity tests. Environmental Toxicology and Chemistry, 2000, 19(6), 1589-1596. (SCI; Impact factor = 2.826; Ranking in Environmental Sciences = 52/215 = 24.2%).