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2018年09月04日

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 藍琴臺 教授：
學歷：國立台灣大學醫學院解剖學研究所博士
現職：私立中山醫學大學解剖學科教授兼任解剖科主任
研究：（1）建立迷走─舌下神經雜接動物模式，藉由迷走神經的背側運動核與疑核的不同功能屬性，來探討經迷走─舌下周邊神經雜接後，探討中樞神經塑性的改變；（2）建立睡眠剝奪的動物模式，以探討失眠症對於腦內生理時鐘及其神經迴路運作機制的影響；（3）進行腦缺血合併睡眠剝奪的動物實驗，發現睡眠剝奪對於後繼的腦缺血竟然具有前行制約以及神經保護效應；（4）與北區長庚醫院整形外科合作研究臂神經叢傷害與食道重建。與神經外科合作研究癲癇症與手汗症；（5）目前正與台北榮總神經醫學中心的神經修復科主任鄭宏志醫師合作，共同努力探索在脊髓損傷並予全方位修復術治療後，中樞神經如何進行神經再生與重塑。

研究:

國際期刊 (International Referred Journals) SCI papers (2000-2009)
　
  1.  Lan C.T., J.C. Liu, J.C. Hsu, and E.A. Ling (2000) Different astroglial reaction between the vagal dorsal motor nucleus and nucleus ambiguus following vagal-hypoglossal nerve anastomosis in cats. Brain Research 881:222-226. (NSC88-2314-B-040-014)
  2. Lan C.T., J.C Liu, E.A. Ling, M.H. Cheng, and S.C. Youn (2000) Target-dependent axonal sprouting following vagal-hypoglossal nerve anastomosis in cats. Restorative Neurology and Neuroscience 17:113-124. (NSC89-2314-B-040-007)
  3. Lan C.T., J.C. Hsu, and E.A. Ling (2001) Influence of sleep deprivation coupled with administration of melatonin on the ultrastructure of rat pineal gland. Brain Research 910:1-11. (NSC89-2320-B-040-070)
  4. Hattori Y., D.C.C. Chuang, and C.T. Lan (2001) Sensory restoration of the skin grafts on a free muscle fap -- Experimental rabbit study. Plastic and Reconstructive Surgery 108:132-140. (NSC88-2314-B-182A-015)
  5. Tan B.K., H.C. Chen, F.C. Wei, S.F. Ma, C.T. Lan, L.C. See, and Y.L. Wan (2002) Formation of independently revascularized bowel segments using the rectus abdominis flap: a rat model for jejunal prefabrication. Plastic and Reconstructive Surgery 109:655-663.
  6. Wang H.M., S.C. Youn, M.H. Cheng, and C.T. Lan (2002) Microglial reactions in the pineal gland of sleep-deprived rats with or without melatonin treatment. 中山醫學雜誌 13:59-68. (NSC89-2320-B-040-070)
  7. Hsu J.C., Y.S. Lee, C.N. Chang, H.L. Chuang, E.A. Ling, and C.T. Lan (2003) Sleep deprivation inhibits expression of NADPH-d and NOS while activating microglia and astroglia in the rat hippocampus. Cells Tissues Organs 173: 242-254. (NSC88-2314-B-182A-097 and NSC89-2320-B-040-070)
  8. Lan C.T., J.C. Hsu, C.N. Chang, H.L. Chuang, and E.A. Ling (2003) Synaptic remodeling in the dorsal motor nucleus of the vagus nerve following vagal-hypoglossal nerve anastomosis in the cat. Journal of Comparative Neurology 458:195-207.(NSC88-2314-B-040-014)
  9. Hsu J.C., Y.S. Lee, C.N. Chang, E.A. Ling, C.T. Lan (2003) Sleep deprivation prior to transient global cerebral ischemia attenuates glial reaction in the rat hippocampal formation. Brain Research 984: 170-181.
  10. Lan, C.T., J.C. Hsu, C.Y. Tseng, C.N. Chang, E.A. Ling (2004) Synaptic remodeling in the nucleus ambiguus following vagal-hypoglossal nerve anastomosis in the cat. Brain Research 1013: 60-73.
  11. Chang, H.M.*, Wu, U.I., Lin, T.B., Lan, C.T., Chien, W.C., Huang, W.L. and Shieh, J.Y. (2006) Total sleep deprivation inhibits the neuronal nitric oxide synthase and cytochrome oxidase reactivities in the nodose ganglion of adult rats. Journal of Anatomy 209: 239-250. [SCI, 國科會計畫編號 NSC 93-2320-B040-047]
  12. Chang, H.M.*, Huang, Y.L., Lan, C.T., Wu, U.I., Hu, M.E. and Youn, S.C. (2008) Melatonin preserves superoxide dismutase activity in hypoglossal motoneurons of adult rats following peripheral nerve injury. Journal of Pineal Research 44: 172-180. [SCI, 國科會計畫編號 NSC 94-2320-B040-014; NSC 95-2320-B040-012]
  13. Chang, H.M.*, Mai, F.D., Chen, B.J., Wu, U.I., Huang, Y.L., Lan, C.T. and Ling, Y.C. (2008) Sleep deprivation predisposes liver to oxidative stress and phospholipid damage - a quantitative molecular imaging study. Journal of Anatomy 212: 295-305. [SCI, 國科會計畫編號 NSC 95-2320-B040-012; NSC 96-2320-B040-015] 
  14. Chang, H.M.*, Wu, U.I. and Lan, C.T. (2009) Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats. Journal of Pineal Research 47: 211-220.
  15. Hu, M.E., Tyan, Y.S., Hsu, P.W., Hsu, J.C., Chang, H.M., Ling, E.A. and Lan, C.T.* (2009) Ultrastructural observations on the progress of nerve degeneration and regeneration at the suture site following vagal-hypoglossal nerve coaptation in cats. Cells Tissues Organs 190: 230-245
  16. Chang HM,Liao WC, Sheu JN, Chang CC,Lan CT and Mai FD. (2012, Jun). Sleep Deprivation Impairs Ca2+ Expression in the Hippocampus: Ionic Imaging Analysis for Cognitive Deficiency with TOF-SIMS . microscopy and microanalysis, 18, 425–435. (SCI, 1/10，MICROSCOPY).
  17. Liao WC, Chen CH, Liu CH, Huang MJ, Chen CW, Hung JS, Chou CH, Chen CH, Che MI, Chang HM, Lan CT, Huang HC, Tseng GF, Shyu MK, Huang MC. (2012, Dec). Expression of GALNT2 in human extravillous trophoblasts and its suppressive role in trophoblast invasion . Placenta, 33:1005-1011. (SCI, 7/79，OBSTETRICS & GYNECOLOGY).
  18. Chang HM, Shyu MK, Tseng GF, Liu CH, Chang HS, Lan CT, and Liao WC. (2013) Neuregulin Facilitates Nerve Regeneration by Speeding Schwann Cell Migration via ErbB2/3-dependent FAK Pathway. Plos one , January 2013 Volume 8 Issue 1 e53444. (SCI, 12/84,BIOLOGY).

　


國內學術討論會 (Local Conference Papers) (1999-2005)

  1. Chen S.L., D.C.C. Chuang and C.T. Lan (1999) Nerve-in-vein composite graft as a conduit increases length of the cap that regenerating axons can span. The Fourteenth Joint Annual Conference of Biomedical Sciences P.140. (Oral Presentation)
  2. Hsu J.C. and C.T. Lan (2002) Sleep deprivation affects NO regulation and glial reactions in the rat hippocampus. The Seventeenth Joint Annual Conference of Biomedical Sciences O.19. (Oral Presentation)
  3. Hsu J.C. and C.T. Lan (2002) Sleep deprivation attenuates NO synthesis and microglial reaction induced by transient global cerebral ischemia in the rat hippocampal formation. The Seventeenth Joint Annual Conference of Biomedical Sciences S.36. (Oral Presentation)
    　


國際學術討論會 (International Conference Papers) (1999-2005)

  1. Hsu J.C., C.T. Lan, and E.A. Ling (2000) Effects of melatonin on the pineal gland of sleep-deprived rats. Proceedings of the 7th Asia-Pacific Electron Microscopy Conference - Life Sciences. LS045:231-232. (Poster Presentation)
  2. Lan C.T., J.C. Hsu, and E.A. Ling (2000) Differences in astroglial reaction between dorsal motor nucleus of the vagus and nucleus ambiguus following vagal-hypoglossal nerve anastomosis in cats. Proceedings of the 7th Asia-Pacific Electron Microscopy Conference - Life Sciences.LS048:237-238. (Poster Presentation)
  3. Hsu J.C., Y.S. Lee, C.N. Chang, H.L. Chuang, E.A. Ling, and C.T. Lan (2002) Sleep deprivation affects NITRIC OXIDE synthesis and glial reactions in the rat hippocampus. The 5th European Meeting on Glial Cell Function in Health and Disease. (Poster Presentation)



著書
SOBOTTA ATLAS OF HUMAN ANATOMY. 12th Edition. (中譯版) (藍琴臺副教授總編輯，合記書局有限公司代理)


　

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