廖雅芳 博士班學生 (Ya-Fan LIAO)

Personal Data

Sex

Female

E-mail

alice6803@yahoo.com.tw

Education

2006

A Candidate for Doctor's Degree, Life Sciences, National Chung-Hsing University, Taichung, Taiwan

2003

M.S., Immunology, Chung-Shan Medical University, Taichung, Taiwan

1999

Junior Bachelor, Medical Technology, Chung Hwa College of Medical Technology, Tanian, Taiwan

Research and Professional Experience

2003-present

A Candidate for Doctor's Degree, Department of Life Sciences, National Chung-Hsing University, Taichung, Taiwan. Advisor: Hui-Chih Hung Ph.D. The role of ornithine decarboxylase in leukocyte differentiation.

2001-2003

M.S. Thesis, Institute of Immunology, Chung-Shan Medical University, Taichung, Taiwan. Advisor: Guang-Yaw Liu Ph.D. Human ornithine decarboxylase prevents apoptosis by Rottlerin in human leukemia HL60 cells.

1999-2001

Medical Technologist, Hongren Hospital, Changhua, Taiwan.

1994-1999

Junior Bachelor Degree, Department of Medical Technology, Chung Hwa College of Medical Technology, Tanian, Taiwan.

 Honours and Awards

2003

M.S. Thesis Award, Institute of Immunology, Chung-Shan Medical University, Taichung, Taiwan.  

1999

Medical Technologist License, Taiwan. 

1999

Junior Bachelor Degree Awards, Chung Hwa College of Medical Technology, Tanian, Taiwan.

Scientific Commissions, Board and Society Memberships

The Chinese Society of Immunology, Taiwan.

The Taiwan Society of Biochemistry and Molecular Biology, Taiwan.

The Chinese Society of cell and Molecular Biology, Taiwan.

 Academic Activity

(1)         Liao YF, Hung HC and Liu GY. Ornithine decarboxylase interferes with tumor necrosis factor-a-mediated matrix metalloproteinase-9 production on macrophage-like differentiation. OP-51, 2006 31st FEBS Congress, Molecular in health & disease, Istanbul, Turkey, June 24-29, 2006. Awarded a FEBS scholarship.

(2)         Liu GY, Liao YF and Hung HC. Inducible antizyme, natural ornithine decarboxylase inhibitor, affects apoptotic cell death. 2006 31st FEBS Congress, Molecular in health & disease, Istanbul, Turkey, June 24-29, 2006.

(3)         Lin CY, Liao YF, Hsu PC, Hung HC and Liu GY. Enhancement of peptidylarginine deiminase 4 (PAD4) enzymatic activity assists apoptosis. OP-19, 2006 31st FEBS Congress, Molecular in health & disease, Istanbul, Turkey, June 24-29, 2006.

(4)         Liao YF, Hsieh MC, Hung HC and Liu GY. Overexpression of antizyme induces Jurkat T cell apoptosis. 第二十一屆生物醫學聯合學術年會2006年3月18日

(5)         Hsieh MC, Liao YF, Hung HC and Liu GY. Antizyme inhibitor interferes with cell growth in human acute leukemia Jurkat T cell. 第二十一屆生物醫學聯合學術年會: 2006年3月18日

(6)         Hsieh HC, Liao YF, Liu GY, Hung HC. Characterization of the enzymatic activity of peptidylarginine deiminase 4: the pathogenic roles of single nucleotide polymorphisms. 第二十一屆生物醫學聯合學術年會: 2006年3月18日

(7)         Lin CY, Liao YF, Liu GY and Hung HC. Elevated peptidylargine deiminase 4 enzyme activity promotes apoptotic cell death. 第二十一屆生物醫學聯合學術年會: 2006年3月18日

(8)         Liao YF, Liu GY and Hung HC. Ornithine decarboxylase interferes with HL-60 cells differentiation-induced by 12-O-tetradecanoylphorbol-13-acetate. 2005 The Taiwan Society Biochemistry and Molecular Biology, Ilan, Taiwan: From Genomics to Biotechnology, page 57, September 8-9, 2005.

(9)         Liao YF, Hsu PC, Tsay GJ, Liu GY and Hung HC. Ornithine decarboxylase represses 12-O-tetradecanoylphorbol-13-acetate-induced matrix metalloproteinase-9 by inhibiting tumor necrosis factor-a. 2005 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, ROC Taipei, Taiwan: 32, November 26-27, 2005.

(10)     Liao YF, Hsu PC, Liu GY, Tsay GJ and Hung HC. A Continous spectrophotometric assay method for peptidylarginine deiminase type IV activity. The Chinese Society of Immunology, Taiwan & The Rheumatology Association, ROC Taipei, Taiwan: 32, November 26-27, 2005.

(11)     Hsu PC, Liao YF, Hung YC, Hung HC, Tsay GJ and Liu GY. Prolaction prevents methothrexate-induced apoptosis by two different ways in HL-60 cells: the relationship between ODC and Bcl-2 upon prolactin stimulation. 2005 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, ROC Taipei, Taiwan:32, November 26-27, 2005.

(12)     Hsu PC, Liao YF, Hung HC, Tsay GJ and Liu GY. Overexpression of peptidylarginine deiminase IV plays a role in apoptosis of human leukemia HL-60 cells and human acute T leukemia Jurkat cells. 2005 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, ROC Taipei, Taiwan:32, November 26-27, 2005.

(13)     Hsieh MC, Hsu PC, Liao YF, Tsay GJ, Hung HC and Liu GY.  Ionomycin provokes peptidylarginine deiminase 4-induced apoptosis in Jurkat T cells. 2005 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, ROC Taipei, Taiwan:32, November 26-27, 2005.

(14)     Liao YF, Liu CC, Hung HC, Tsay GJ and Liu GY. Ornithine decarboxylase (ODC) inhibits 92-kDa type IV collagenase/gelatinase (MMP-9) activation in HL60 cells during differentiation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 2004 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, Taipei, Taiwan ROC: 99-100, December 11-12, 2004.

(15)     Liu CC, Liao YF, Hung HC, Tsay GJ and Liu GY. Ornithine decarboxylase resists cisplatin, etoposide and paclitaxel-induced apoptotic insults in human leukemia HL-60 cells. 2004 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, Taipei, Taiwan ROC: 100, December 11-12, 2004.

(16)     Hung YC, Hsu PC, Liao YF, Hung HC, Tsay GJ and Liu GY. Ornithine decarboxylase prevents methotrexate-induced apoptosis by reducing intracellular reactive oxygen species. 2004 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, Taipei, Taiwan ROC: 98-99, December 11-12, 2004.

(17)     Hung YC, Hsu PC, Liao YF, Hung HC, Tsay GJ and Liu GY. Ornithine decarboxylase prevents tumor necrosis factor alpha-induced apoptosis by decreasing intracellular reactive oxygen species. 2004 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, Taipei, Taiwan ROC: 25-26, December 11-12, 2004.

(18)     Hsu PC, Hung YC, Liao YF, Hung HC, Tsay GJ and Liu GY. Increasing expression and activity of ornithine decarboxylase is a way to prevent methotrexate-induced apoptosis by prolactin in HL-60 cells. 2004 Joint Meeting of The Chinese Society of Immunology, Taiwan & The Rheumatology Association, Taipei, Taiwan ROC: 40-41, December 11-12, 2004.

 Publication

(1)         Liu GY, Liao YF, Hsu PC, Chang WH, Hsieh MC, Lin CY, Hour TC, Kao MC, Tsay GJ and Hung HC. Antizyme, a natural ornithine decarboxylase inhibitor, induces apoptosis of haematopoietic cells through mitochondrial membrane depolarization and caspases' cascade. Apoptosis (Epub ahead of print) (SCI: 4.54; 51/261)

(2)         Hsu PC, Hour CT, Liao YF, Hung YC, Liu CC, Chang WH, Kao MC, Tsay GJ, Hung HC and Liu GY. Increasing Ornithine Decarboxylase Activity Is Another Way of Prolactin Preventing Methotrexate-Induced Apoptosis: CROSSTALK BETWEEN ODC AND BCL-2. Apoptosis 11(3):389-99, 2006. NSC 93-2320-B-040-048 and NSC 94-2745-B-040-005-URD (SCI: 4.54; 51/261)

(3)         Liu GY, Liao YF, Chang WH, Liu CC, Hsieh MC, Hsu PC, Tsay GJ and Hung HC. Overexpression of peptidylarginine deiminase IV features in apoptosis of haematopoietic cells. Apoptosis 11(2):183-96, 2006. NSC 93-2320-B-040-048 and NSC 94-2745-B-040-008-URD (SCI: 4.54; 51/261)

(4)         Liao YF, Hsieh HC, Liu GY and Hung HC. A Continuous Spectrophotometric Assay Method for Peptidylarginine Deiminase Type 4 Activity. Anal. Biochem. 347:176-181, 2005. NSC 93-2745-B-040-005-URD (SCI: 2.37; 16/70)

(5)         Liao YF, Hung YC, Chang WH, Tsay GJ, Hour TC, Hung HC and Liu GY. The PKC delta inhibitor, rottlerin, induces apoptosis of haematopoietic cell lines through mitochondrial membrane depolarization and caspases’ cascade. Life Sci. 77(6):707-719, 2005. NSC 92-2320-B-040-057, NSC 92-2815-C-040-002-B, NSC 93-2320-B-040-048, NSC 93-2745-C-040-005-URD (SCI: 2.16; 69/187)

(6)         Liu GY, Hung YC, Hsu PC, Liao YF, Chang WH, Tsay GJ and Hung HC. Ornithine decarboxylase prevents tumor necrosis factor alpha-induced apoptosis by decreasing intracellular reactive oxygen species. Apoptosis 10(3):569-581, 2005. NSC 93-2320-B-040-048 and NSC 93-2745-B-040-005-URD (SCI: 4.54; 19.5%)

(7)         Huang CC, Hsu PC, Hung YC, Liao YF, Liu CC, Hour CT, Kao MC, Tsay GJ, Hung HC and Liu GY. Ornithine decarboxylase prevents methotrexate-induced apoptosis by reducing intracellular reactive oxygen species production. Apoptosis 10(4):895-907, 2005. NSC 93-2320-B-040-048 and NSC 93-2745-B-040-005-URD (SCI: 4.54; 51/261)