Name

Hsiao-Yun Chen

E - mail

p1986752020@gmail.com

Thesis title

A study comparing gender differences on absolute and relative index of international lung adenocarcinoma incidence rates

Publication

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Abstract

Objective: The purpose of this study was to determine the gender comparison of lung adenocarcinoma for different age groups and period by use of absolute and relative index. Methods: Data was obtained from the IARC (International Agency for Research on Cancer) of the World Health Organization(WHO) the publication Cancer Incidence in Five Continents sixth to the eighth edition and the Taiwan Department of Health Cancer registration system provides total incidence of lung adenocarcinoma data, totally 18 countries(1983-1987 and 1993-1997). We calculated the directly age-standardized incidence rate (ASIR) of lung adenocarcinoma, age (30-44, 45-64 and 65-79) specific incidence rate, and the age- and period- increasing rate of lung adenocarcinoma in differences age groups and periods. Further we used the Poisson regression to estimate the relative risk and 95% confidence interval (95% CI).
Results: In 1983-1987 and 1993-1997, the ASIR raised from 4.94 to 8.27 among males and 3.05 to 6.52 among females per 100,000 persons in Taiwan. The ASIR among males was higher than females except Iceland and the male to females ratio in most countries declined as age increased. In Taiwan, used the age in 30-44 as baseline, in 1983-1987 at 45-64 and 65-79 years old in males of the increasing rate of lung adenocarcinoma was 965.12 % and 2468.22 %, females was 622.31% and1279.34%. Most countries the lung adenocarcinoma increasing rate of males is higher than females, except India and Spain in 1983-1987. Contrary, in the period effect, Taiwanese age-standardized lung adenocarcinoma increasing rate was 67.41% among males and females was 113.77%, most countries the increasing rate of females in different age groups is higher than the males.
Conclusion: In the absolute comparison, females have not higher risk to develop lung adenocarcinoma than males. But in relative comparison, females have a higher relative risk of lung adenocarcinoma in period effect; Males have higher relative risk of lung adenocarcinoma in age effect.