張 浤 榮 醫 師

Horng-Rong Chang, MD, PhD

現任

教育部部定教授 (教字第020598號)

中山醫學大學醫學系專任教授

中山醫學大學附設醫院腎臟科主任

台灣腎臟醫學會理事

台灣移植醫學會理事

台灣腎臟醫學會腎臟移植推廣委員會副主任委員

台灣腎臟醫學會公共事務委員會副主任委 員

台灣腎臟醫學會透析護理人員訓練醫院評鑑委員會副主委

台灣腎臟醫學會專科醫師甄審委員會委員

台灣腎臟醫學會醫療政策協調委員會委員

台灣腎臟醫學會腎臟病理登錄委員會委員

台灣腎臟醫學會雜誌編輯委員

腎臟與透析雜誌副主編

中華民國腎臟專科醫師

中華民國內科專科醫師

地址：台中市南區建國北路一段110號  中山醫學大學附設醫院腎臟科

電話：04-24739595 分機 32620、34704、34711

傳真：04-24739595  分機 32624

電子信箱：chrcsmu@gmail.com

學歷

1986~1993    高雄醫學大學  醫學士

2003~2006   中山醫學大學  醫學博士

住院醫師訓練

1993            秀傳紀念醫院  內科住院醫師

1994~1996    埔里榮民醫院  內科住院醫師

1996~1999    台中榮民總醫院  內科住院醫師

1999~2001    台中榮民總醫院  腎臟科住院總醫師

專科證照

1993              醫師檢覈考試合格

1993              公職醫師高考合格

1997~迄今    台灣內科專科醫師

2001~迄今    台灣腎臟專科醫師

會員

1997~迄今        台灣內科醫學會會員

2001~迄今        台灣腎臟醫學會會員

2001~迄今        台灣移植醫學學會會員

        2009~迄今        台灣泌尿腫瘤學會會員

學經歷

2000~2002       國防醫學院  臨床兼任講師

2001~2007       中山醫學大學附設醫院腎臟科  主治醫師

2001~2006       中山醫學大學醫學系  講師

2007~2009       中山醫學大學醫學研究所  助理教授

2007~迄今       中山醫學大學附設醫院  腎臟科主任

2008, 02           東京醫科大學八王子醫療中心臟器移植外科及腎臟科  訪問學者

2009~2013       中山醫學大學醫學研究所  副教授

2013~~2014     中山醫學大學醫學研究所  教授

2011-2014         台灣移植醫學會監事

2014~迄今       中山醫學大學醫學系教授

五年內論文發表 

1.         Hsu YH, Huang HP, Chang HR (2019, Mar). The uremic toxin p-cresol promotes the invasion and migration on carcinoma cells via Ras and mTOR signaling. Toxicol In Vitro, 58:126-131.. Ditmanson Medical Foundation Chia-Yi Christian Hospital and Chung Shan Medical University Hospital: CSMU-CYCH-103-02. 本人為通訊作者.

2.         Chang CY, Chang HR, Lin HC, Chang HH. (2018, Mar). Comparison of Renal Function and Other Predictors in Lacto-Ovo Vegetarians and Omnivores With Chronic Kidney Disease . Journal of the American College of Nutrition, 13:1-6 .

3.         Hung TW, Chen PN, Wu HC, Wu SW, Tsai PY, Hsieh YS, Chang HR. (2017, Aug). Kaempferol Inhibits the Invasion and Migration of Renal Cancer Cells through the Downregulation of AKT and FAK Pathways. . International Journal of Medical Sciences, 14(10):984-993.. Chung Shan Medical University Hospital: CSH-2015-C-024. 本人為通訊作者. [Co-correspondence] .

4.         Wu SW, Chen PN, Lin CY, Hsieh YS, Chang HR (2017, Jul). Everolimus suppresses invasion and migration of renal cell carcinoma by inhibiting FAK activity and reversing epithelial to mesenchymal transition in vitro and in vivo . Environmental Toxicology, 32(7):1888-1898.. MOST 104-2314-B-040-011. 本人為通訊作者. [Co-correspondence] .

5.         Chang HR, Chang YC, Shao SY, Huang HH.   (2017, Jun). Mulberry Anthocyanins Induce Leukemia WEHI-3 Cells Apoptosis, Autophagy, Differentiation and prolong leukemic mice survival. International Journal of Contemporary Research and Review, 8(6),20211-20224. Chung Shan Medical University Hospital: CSH-2013-C-028. 本人為第一作者.

6.         Hsiao KC, Huang JY, Lee CT, Hung TW, Liaw YP, Chang HR (2017, Apr). Different impact of aspirin on renal progression in patients with predialysis advanced chronic kidney disease with or without previous stroke. European Journal of Internal Medicine, S0953-6205(16)30405-8. Chung Shan Medical University Hospital: CSH-2011-D-003. 本人為通訊作者. [Co-correspondence].

7.         Wang SC, Sung WW, Kao YL, Hsieh TY, Chen WJ, Chen SL, Chang HR. (2017, Jan). The gender difference and mortality-to-incidence ratio relate to health care disparities in bladder cancer: National estimates from 33 countries. . Sci Rep, 28;7(1):4360.. 本人為通訊作者.

8.         Hung TW, Tsai JP, Lin SH, Lee CH, Hsieh YH, Chang HR (2016, Dec). Pentraxin 3 Activates JNK Signaling and Regulates the Epithelial-To-Mesenchymal Transition in Renal Fibrosis. Cellular Physiology and Biochemistry, 2016;40(5):1029-1038. Chung Shan Medical University Hospital: CSH-2013-C-009. 本人為通訊作者. [Co-correspondence].

9.         Tsai ML, Yen CC, Lu FJ, Ting HC, Chang HR. (2016, Sep). Environmentally relevant concentration of arsenic trioxide and humic acid promoted tumor progression of human cervical cancer cells: In vivo and in vitro studies. . Environmental Toxicology, 31:1121-32. NSC 93-2745-B-040-001-URD. 本人為通訊作者.

10.     Wu SW, Liou JH, Yeh KT, Hung TW, Chang HR. (2016, Aug). The Prevalence and Prognostic Significance of Polyomavirus Infection in Patients with Urothelial Carcinoma of the Bladder. Urology Journal, 13(4):2773-8. Chang Shan Medical University Hospital: (CSH-2012-C-013. 本人為通訊作者. [Co-correspondence].

11.     Yang TY, Liaw YP, Huang JY, Chang HR, Chang KW, Ueng KC. (2016, Jun). Association of Sitagliptin with cardiovascular outcome in diabetic patients: a nationwide cohort study.. Acta Diabetol , 53(3):461-8.

12.     Chiu PF, Tsai CC, Wu CL, Yang TY, Liou HH, Chen HL, Kor CT, Chang CC, Chang HR. (2016, Mar). Trajectories of Serum Albumin Predict Survival of Peritoneal Dialysis Patients: A 15-year Follow-Up Study. Medicine (Baltimore), 95(12):e3202.. 本人為通訊作者. [Co-correspondence].

13.     Hsiao KC, Tsai JP, Yang SF, Lee WC, Huang JY, Chang SC, Hso CS, Chang HR. (2016, Jan). MMP-2 serum concentrations predict mortality in hemodialysis patients: a 5-year cohort study. Clin Chim Acta , 452:161-166 . NSC 101-2314-B-040-003. 本人為通訊作者.

14.     Tsai ML, Huang CN, Lai YR, Chang HR, Chiou JY (2015, Apr). The effect of benzodiazepine and nonbenzodiazepine prescriptions for diabetes mellitus type 2 in elderly Taiwanese with depressive symptoms. Psychogeriatrics, 2015 Apr 27. doi: 10.1111/psyg.12126.. 本人為通訊作者. [Co-correspondence] .

15.     Hsiao KC, Chao WR, Tsai JP, Wen MC, Lian JD, Lee WC, Huang JY, Chang SC, Chang HR (2014, Nov). Dysregulation of interleukin 23 receptor expression in kidney allografts associated with composite outcome . Journal of Cytology & Histology, S4:017. doi: 10.4172/2157-7099.. 本人為通訊作者.

16.     Chiu PF, Wu CL, Huang CH, Liou HH, Chang CB, Chang HR, Chang CC (2014, Sep). Lower blood glucose and variability are associated with earlier recovery from renal injury caused by episodic urinary tract infection in advanced type 2 diabetic chronic kidney disease.. PLoS One, 2014 Sep 26;9(9):e108531. . Changhua Christian Hospital: 97CCHIRP-31.

17.     Wang CJ,Tsai JP,Yang SF, Lian JD, Chang HR (2014, Jul). Stromal Cell-Derived Factor 1 Gene Polymorphism Is Associated with Susceptibility to Adverse Long-Term Allograft Outcomes in Non-Diabetic Kidney Transplant Recipients . International Journal of Molecular Sciences, 15(7), 12495-12506. (SCI, 48/152 CHEMISTRY, MULTIDISCIPLINARY). 本人為通訊作者.

18.     Tsai ML, Huang HP, Hsu JD, Lai YR, Hsiao YP, Lu FJ, Chang HR (2014, May). Topical N-Acetylcysteine Accelerates Wound Healing in vitro and in vivo via PKC/Stat3 Pathway . International Journal of Molecular Science, 15; 7563-7578. (SCI, 48/152 CHEMISTRY, MULTIDISCIPLINARY.). MOST 98-2314-B-040-004-MY3. 本人為通訊作者.

19.     Chiu PF, Huang CH, Liou HH, Wu CL, Chang CB, Chang CC, Chang HR (2014, Apr). Lower-dose warfarin delays renal progression and prolongs patient survival in patients with stage 3-5 chronic kidney disease and nonvalvular atrial fibrillation: a 12-year follow-up study. International journal of clinical pharmacology and therapeutics, DOI 10.5414/CP202053. (SCI, 199/261, PHARMACOLOGY & PHARMACY). 本人為通訊作者. [Co-correspondence].

(B)  五年內研討會發表 

1.         Chang HR, Chen PN, Hsieh YS. (2019, Apr). Thymoquinone induces cell death in human renal carcinoma cells via apoptosis and autophagy. The 56th ERA-EDTA Congress, Budapest, Hungary. MOST 105-2314-B-040-014-MY3. 本人為第一作者.

2.         Chang HR, Hsu YH, Huang HP (2015, Dec). Uremic Toxin with P-Cresol Promotes Invasion and Migration of Urothelial Carcinoma Cells. Scientific Congress and Annual Meeting, 2015 Taiwan Society of Nephrology , Kaohsiung. 本人為第一作者、通訊作者.

3.         Hsiao KC, Tsai JP, Chang HR (2014, Dec). Matrix Metalloproteinase-2 is a Non-Inferior Prognostic Marker than Albumin in Hemodialysis patient: A 5-year Cohort Study. 2014 Annual Meeting of Taiwan Society of Nephrology, Taipei. 本人為通訊作者.

4.         Hsieh MH, Tsai JP, Chien JT, Chang HR (2014, Dec). Adiponectin is Associated with Osteoporosis in Hemodialysis Patients. 2014 Annual Meeting of Taiwan Society of Nephrology, Taipei. 本人為通訊作者.

5.         Hung TW, Tsai JP, Chang HR (2014, Dec). Geriatric Nutritional Risk Index Is a Non-inferior Prognostic Marker than Albumin in Hemodialysis Patients: A 5-year Cohort Study. 2014 Annual Meeting of Taiwan Society of Nephrology, Taipei. 本人為通訊作者.

6.         Tsai JP, Chang HR (2014, Dec). Osteopontin is Negatively Associated with Metabolic Markers in Hemodialysis Patients. 2014 Annual Meeting of Taiwan Society of Nephrology, Taipei. 本人為通訊作者.

7.         Tsai PY, Tsai JP, Chang HR, Lian JD (2014, Dec). Stromal Cell Derived Factor 1 Is Associated with Inflammatory and Nutritional Markers in Hemodialysis Patients. 2014 Annual Meeting of Taiwan Society of Nephrology, Taipei.

六、歷年研究計畫

2019/04/26更新