中山醫學大學應用化學系   陳建宏教師簡介

研究領域  學經歷  研究興趣  研究計畫

學術著作  榮譽與得獎  聯絡方式 English Version

　

  陳 建 宏  Chien-Hong Chen

　

           副教授     Associate Professor

 

         研究領域

無機化學、有機金屬和無機生物化學

   

學經歷

2011/2 -  迄 今   中山醫學大學應用化學系 副教授
2006/8 - 2011/1   中山醫學大學應用化學系 助理教授 
2005/8 - 2006/7   國立清華大學化學系 博士後研究 
2002/9 - 2005/7   國立清華大學化學系 理學博士 
2001/8 - 2002/7   台北縣三重市永福國民小學 教師 
2000/9 - 2001/6   南投縣草屯鎮南開技術學院 兼任講師 
2000/4 - 2001/7   國立彰化師範大學化學系 研究助理 
1996/9 - 1998/6   國立彰化師範大學科學教育研究所 理學碩士 
1992/9 - 1996/6   國立彰化師範大學化學系 理學士

　

研究興趣 (生物無機化學) (簡介)

       ¨ 含鎳酵素及晴水解酵素之活性中心結構之模擬合成(簡介)

       ¨ 以金屬酵素模型化合物探討金屬酵素之催化機制 (簡介)

       ¨ 含過渡金屬之一氧化氮釋出劑及一氧化氮捕捉劑之化合物設計及探 討(簡介)

研究計畫

國科會研究計畫

        

u  以含鐵、錳硝基化合物為一氧化氮供給劑及其催化一氧化氮轉換之研究(1/2) (95-2120-M-040-001-) 2006/10/01 ~ 2007/07/31

u  以含鐵、錳硝基化合物為一氧化氮供給劑及其催化一氧化氮轉換之研究 (2/2)(96-2113-M-040-001-) 2007/08/01 ~ 2008/07/31

u  含鐵、錳硝基化合物之合成及反應性探討及其做為一氧化氮供給劑與催化一氧化氮轉換之研究(97-2113-M-040-002-MY2) 2008/08/01 ~ 2010/07/31

u  雙亞硝醯基鐵化合物之合成，反應性研究及其電子結構與作為一氧化氮傳遞劑效率探討(99-2119-M-040-001-) 2010/08/01 ~ 2011/07/31

u  新穎双亞硝醯基鐵化合物之合成、結構、反應性及其電子結構之探討(100-2113-M-040-004-MY2) 2011/08/01 ~ 2013/07/31

　

　

 

實驗室研究設備

    ▲ Glove-box

        ▲ FTIR

        ▲ Schlenk lines and vacuum lines

學術著作

A. 期刊論文

1.    Jheng-Hong Wang, and Chien-Hong Chen*. “New Members of the {Fe(NO)2}10 Dinitrosyliron Complexes Bound with [Thiolate, Thiolate] and [Amide, Amide] Ligations” Inorg. Chem. 2010, 49, 7644-7646. (IF: 4.657  D3/44; 6.8%)

2.    Chien-Hong Chen, and Wen-Feng Liaw. “IRON–CYANOCARBONYL COMPLEXES [PPN][Fe(CO)4(CN)] AND [PPN][FeBr(CO)3(CN)2]” Inorganic Syntheses 2010, 35, 129-132.

3.    Chien-Ming Lee,* Chien-Hong Chen, Fu-Xing Liao, Ching-Han Hu, and Gene-Hsiang Lee. “Mononuclear NiIII-Alkyl Complexes (Alkyl = Me and Et): Relevance to the Acetyl-CoA Synthase and Methyl-CoM Reductase” J. Am. Chem. Soc. 2010, 132, 9256-9258. (IF: 8.580  D7/138)

4.    Chien-Hong Chen*, Show-Jen Chiou*, Hsuan-Yin Chen. “Dinuclear [{Fe(NO)2}10-{Fe(NO)2}10] Dinitrosyl Iron Complex withThiolate-CO-Bridged Ligands” Inorg. Chem. 2010, 49, 2023-2025. (IF: 4.657  D3/44; 6.8%)

5.    Chien-Hong Chen, Chang-Chih Hsieh, Hon Man Lee, and Yih-Chern Horng*. “trans-Diacetonitriletetrakis(1H-pyrazole-kN2)nickel(II) dinitrate” Acta Crystallogr., Sect. E: Struct. Rep. Online 2009, E65, m1680 (IF: 0.411  D24/25; 96%)

6.    Chien-Hong Chen*, Yi-Chieh Ho, and Gene-Hsiang Lee. “Synthesis and Reactivity of the Five-coordinate {Fe(NO)2}9 [(TMEDA)Fe(NO)2I]” J. Organomet. Chem. 2009, 694, 3395-3400. (IF: 2.347  D14/44; 31.8%)

7.    Chien-Hong Chen, Gene-Hsiang Lee, and Wen-Feng Liaw＊. “Mononuclear [Ni = 2 \* ROMAN II(L)(P-(o-C6H4S)2(o-C6H4SH))]0/1–  (L = Thiolate, Selenolate, PPh3, and Cl) Complexes with Intramolecular [Ni－S…H－S]/[Ni…H－S] Interactions Modulated by the Coordinated Ligand L: Relevance to the [NiFe] Hydrogenases” Inorg. Chem. 2006, 45, 2307-2316. (IF: 4.657  D3/44; 6.8%)

8.    Chien-Ming Lee, Chien-Hong Chen, Hao-Wen Chen, Jo-Lu Hsu, Gene-Hsiang Lee, and Wen-Feng Liaw＊. “Nitrosylated Iron-Thiolate-Sulfinate Complexes with {Fe(NO)}6/7 Electronic Cores: Relevance to the Transformation between the Active and Inactive NO-Bound Forms of Fe-Containing Nitrile Hydratases” Inorg. Chem. 2005, 44, 6670-6679. (IF: 4.657  D3/44; 6.8%)

9.    Chien-Ming Lee, Chien-Hong Chen, Shyue-Chu Ke, Gene-Hsiang Lee and Wen-Feng Liaw＊. “Mononuclear Nickel(III) and Nickel(II) Thiolate Complexes with Intramolecular S-H Proton Interacting with Both Sulfur and Nickel: Relevance to the [NiFe]/[NiFeSe] Hydrogeanses” J. Am. Chem. Soc. 2004, 126, 8406-8412. (IF: 8.580  D7/138)

10.  Chien-Hong Chen, Yung-Su Chang, Chien-Yeh Yang, Tai-Nan Chen, Chien-Ming Lee and Wen-Feng Liaw＊. “Preparative and Structural Studies on Iron(II)-Thiolate Cyanocarbonyls: Relevance to the [NiFe]/[Fe]-Hydrogenases” Dalton Trans. 2004, 137-143. (IF: 4.081  D7/44; 15.9%)

11.  Chien-Hong Chen, Li-Chun Wang and Wen-Feng Liaw＊. “Preparative and Structural Studies on Ruthenium( = 2 \* ROMAN II)-Thiolate Cyanocarbonyls: Comparision to the [Fe(CO)x(CN)y(SR)z]n- Coordination Modes of Active Sites of Hydrogenases” J. Chin. Chem. Soc. 2004, 51, 1121-1126. (IF: 0.653  D96/138; 69.6%)

12.  Chien-Ming Lee, Chien-Hong Chen, Chung-Hung Hsien, Amitava Dutta and Gene-Hsiang Lee. “Iron-Nitrosyl Sulfinate Complexes: Relevance to the Fe-Containing Nitrile Hydratatses” J. Inorg. Biochem. 2003, 96, 176. (IF: 3.252  D9/44; 20.5%)

13.  Chien-Hong Chen, Chien-Ming Lee, Chung-Hung Hsieh and Wen-Feng Liaw＊. “Bioinorganic Chemistry” Chemistry (The Chinese Chem. Soc., Taipei) 2003, 61, 79-86.

14.  Wen-Feng Liaw＊, Jiun-Hung Lee, Hung-Bin Gau, Chien-Hong Chen, Shiou-Ju Jung, Chen-Hsiung Hung, Wen-Yuan Chen, Ching-Han Hu and Gene-Hsiang Lee. “Five-Coordinate and Six-Coordinate FeII(CN)2(CO)x-Thiolate Complexes (x=1, 2): Synthetic Advances for Iron Sites of [NiFe] Hydrogenases” J. Am. Chem. Soc. 2002, 124, 1680-1688. (IF: 8.580  D7/138)

15.  Wen-Feng Liaw＊, Chien-Hong Chen, Chien-Ming Lee, Gene-Hsiang Lee and Shie-Ming Peng. “Distorted Square Planar Nickel(II)-Carbonyl Complexes Containing Terminal Thiolate/Selenolate Ligands” J. Chem. Soc., Dalton Trans. 2001, 138-143. (IF: 4.081  D7/44; 15.9%)

16.  Wen-Feng Liaw＊, Jiun-Hung Lee, Hung-Bin Gau, Chien-Hong Chen, and Gene-Hsiang Lee. “Synthesis and Reactivity of fac-[Fe(CO)3(SR)3]- (R= C7H4SN, C4H3S, C4H2O-o-CH3) and Heterotrmetallic Fe(II)-Ni(II)-Fe(II) Thiolate Complexes” Inorg. Chim. Acta 2001, 322, 99-105. (IF: 2.322  D17/44; 38.6%)

17.  Wen-Feng Liaw＊, Jiun-Hung Lee, Hung-Bin Gau, Chien-Hong Chen, Shiou-Ju Jung, Wen-Yuan Chen, Ching-Han Hu, and Chen-Hsiang Hung. “Five-Coordinate and Six-Coordinate FeII(CN)2(CO)x-Thiolate Complexes (x=1, 2): Synthetic Advances for Iron Sites of [NiFe] Hydrogenases” J. Inorg. Biochem. 2001, 86, 315. (IF: 3.252  D9/44; 20.5%)

18.  Wen-Feng Liaw＊, Nan-Hung Lee, Chien-Hong Chen, Chien-Ming Lee, Gene-Hsiang Lee and Shie-Ming Peng. “Dinuclear and Mononuclear Iron(II)-Thiolate Complexes with Mixed CO/CN- Ligands: Synthetic Advances for Iron Sites of [Fe]-only Hydrogenases” J. Am. Chem. Soc. 2000, 122, 488-494. (IF: 8.580  D7/138)

19.  Wen-Feng Liaw＊, Chien-Hong Chen, Chien-Ming Lee, Ging-Yi Lin, Chao-Yi Ching, Gene-Hsiang Lee and Shie-Ming Peng. “Heterotrinuclear Complexes Containing a Hexa-selenolate-zinc(II), -cadmium(II), -nickel(II) and –iron(II) Core Individually: Crystal Structures of [(CO)3Fe(μ-SePh)3M(μ-SePh)3Fe(CO)3] (M=Zn, Cd, Ni, Fe) and [Fe(CO)2(phen)(SePh)2] (phen= 1, 10-phenanthroline)” J. Chem. Soc., Dalton Trans. 1998, 353-358. (IF: 4.081  D7/44; 15.9%)

20.  Wen-Feng Liaw＊, Chien-Hong Chen, Gene-Hsiang Lee, Shie-Ming Peng. “The Interconversion of Complexes [Fe(CO)4(SC5H4N)]-, cis-Fe(CO)2(SC5H4N)2, and [Fe(SC5H4N)3]-“ Organometallics 1998, 17, 2370-2372. (IF: 4.204  D4/44; 9.1%)

　

Ｂ．研討會論文

榮譽與得獎

   斐陶斐榮譽學會會員, 彰化師範大學, 1998.

聯絡方式

電 話: 04-2473-0022 轉 12219或11892

傳 真: 04-2324-8189

地 址:台中市402南區建國北路一段110號應用化學系

       Office:正心樓1255a

       Laboratory: 張不大樓D203

E-mail : cchwind@csmu.edu.tw 

　

　

　

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